NEW YORK — Tomorrow afternoon, the Red Sox will play their final regular-season game at Yankee Stadium, though it’s doubtful that Sox players will find much significance in the occasion.

For one thing, player movement being what it is, most players don’t stay in one place long enough to develop an attachment or appreciation for any one ballpark. For another, modern-day players are a decidedly unsentimental lot.

But quite apart from the ballpark’s long and glorious history, Yankee Stadium should be remembered fondly by Red Sox players and fans alike. It is, after all, where the fortunes of the franchise changed for the better.

For decades, of course, Yankee Stadium was the Red Sox’ personal House of Horrors. Where the Red Sox were concerned, whatever could go wrong, invariably did.

The 1949 pennant slipped out of their hands here. Bill Lee’s career was effectively ended here in 1976, his left shoulder shredded in a pig pile of players. And, of course, there was Game Seven of the 2003 American League Championship Series, perhaps the cruelest loss of all.

But a mere 369 days later, the Red Sox turned the next year’s ALCS on its head, and with it, the course of team history. When they capped the greatest comeback in baseball history by rallying from a 3-0 deficit in October 2004, the Red Sox shed the negativity and fatalism that had shrouded the franchise for nearly a century.

That they did so at Yankee Stadium made the comeback all the more sweet. Had the Red Sox beaten the Minnesota Twins en route to their first championship in 86 years, it wouldn’t have been nearly as affirming.

Beating the Yankees, and clinching the pennant on their rivals’ turf, delivered a real closure. If the Red Sox, operating with no margin for error, could win the final two games of a playoff series to take the pennant in the Bronx, there was clearly nothing they couldn’t do.

And so it’s been. The Sox followed their 2004 World Series victory with another last October. Since vanquishing the Yanks in the 2004 ALCS, the Red Sox are 15-6 in the postseason. They are a perfect 8-0 in World Series games.

No longer are they taunted with chants of “1918!” here. To be sure, Yankee fans have history on their side, but not recent history. The Sox have won two titles since the Yankees last won one.

Naturally, the Yankees aren’t running from their glorious history. The new ballpark, nearing completion across the street, will in some ways be a virtual replica of the current one — the same field dimensions, the same spacious foul territory behind home plate, the same monuments beyond the outfield fence.

But not everything will make the journey across 161st Street. The memories, the history and, most intangibly, the aura will be left behind. Not even the most accomplished architects can relocate a ballpark’s soul.

The new stadium will have all the modern amenities, and offer them all at inflated prices. Want the best seats, closest to the action? That will be $2,500, per ticket, per game, please. And you’ll have to buy a minimum of four. Grand total for a single season: $810,000.

The Yankees, already baseball’s most profitable team, will be richer still in their new home and that economic might is likely to manifest itself with more spending. Somewhere, as you read this, an XXL pinstriped uniform is being readied for free agent-to-be CC Sabathia.

Other teams might be intimidated by the flexing of their financial muscle, but the Red Sox won’t be. They can’t spend with the Yankees, but they can spend plenty enough, as the last few seasons have demonstrated.

The Sox might experience a twinge of stadium envy next season when they walk into the new Yankee Stadium for the first time — the Sox themselves having anchored themselves to Fenway for the foreseeable future — but they won’t be cowered by the surroundings. To the Sox, it will be just one more ballpark in a sport rife with them.

They can, however, leave here tomorrow with the satisfaction that they rid themselves of any phobias concerning the old Yankee Stadium. The ballpark that came to be known as The House That Ruth Built was, in its final years of glorious existence, conquered by the team that mistakenly allowed Ruth to go in the first place.

If that’s not karma, it’s at least pretty fitting.

smcadam@projo.com